CRISPR For Gene Treatment

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    CRISPR is one of the most important developments in the science because it can help to find new treatment ways for genetic diseases.




    Every living thing is defined by genes. They tell us how to behave or they basically decide the colour of eyes or hair.

   Clustered Regularly Interspaced Short Palindromic Repeats is also known CRISPR was discovered in 1987 by Yoshizumi Ishino. 

    Scientists got inspired by the immune system of bacteria. This is the natural system that when the virus inside the bacteria, Cas9 protein realise this virus and it gets the virus's RNA genes. Cas9 protein cut the same genes in the target bacteria's genes and paste the virus's RNA genes. When Cas9 protein paste the new genes, it uses "Homology Directed Repair". This process leads to improve the immune system against the virus. Scientists decided to use this process with using Cas9 protein for finding new treatment ways for genetic disorders.

   However, we have some problems with CRISPR because we don't know how the new generation will exist after the gene therapies.
   There are lots of genetic problems and diseases worldwide, common ones are stand out:
🔵 Sickle Cell Anemia
🔵 Marfan Syndrome 
🔵 Fragile X Syndrome
These are the single gene inheritance diseases.

🔴 Alzheimer
🔴 Cancer 
🔴 Heart diseases
These are multifactorial genetic inheritance diseases.

⚫ Down Syndrome 
⚫ Turner Syndrome (45, XO)
⚫ Klinefelter Syndrome (47, XXY)
These are chromosomal abnormalities.  

   In the future, the CRISPR gene editing might be used to create new species and discover the new cure ways. Along with this way, Josiah Zayner who is the Biohacker is trying to help human nature. He established a company, The ODIN. The aim is that everyone should learn genetics. If you want, you can visit his web site.


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